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People will say, Oh, Ive heard the carnivore diet can raise LDL, and often ketogenic and carnivore diets do raise LDL, but as Ive enumerated multiple times on previous podcasts, and I go into in much detail in the book, the evidence that LDL is the main driver of atherosclerosis or is uniquely atherogenic on its own, I think is severely lacking and so what usually happens when people do a carnivore diet from a lipid perspective, is they become much more insulin sensitive and they have a better-looking lipid panel in terms of HDL/triglyceride ratios and fasting insulin, other inflammatory markers usually go down

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Protocol sequencing The sequence is critical

Eight healthy volunteers also made a one-time donation of their blood for preclinical studies to establish a baseline against the clinical trial T2DM subjects

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Experiments have revealed that increasing leucine concentration in fish may cause reduced feed intake and growth [3, 20]