2085-A NOVEL MATRICELLULAR SERUM MARKERS PREDICT LIVER FIBROSIS AND FIBROGENESIS IN PATIENTS WITH NAFLD UNDERGOING BARIATRIC SURGERY Rambabu Surabattula 1 , Pierre Bel Lassen 2,3 , Sudharani Myneni 1 , Judith Aron-Wisnewsky 2,3 , Laurent Genser 3 , Jean-Daniel Zucker 2 , Karine Clment 2,3 and Detlef Schuppan 1,4 , (1)University Medical Center Mainz, (2)Sorbonne Universit, (3)Piti-Salptrire Hospital, (4)Harvard Medical School Background: Obesity is a risk factor for NAFLD and the prevalence of NAFLD in patients eligible for bariatric surgery (BS) can reach 75% to 100%
Figure 6 From our RNAseq analysis, we noted that many of the upregulated genes in the glutathione biosynthesis pathway (including Gclc and Gclm ) are canonical targets of the transcription factor NRF2 (53, 54)
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We start with a full hormone panel via blood draw, then design a treatment plan based on results