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Higher doses produced larger shares of participants achieving at least 15% weight loss, and more reaching 20% or greater

Hong, Y., Downey, T., Eu, K

Healthcare providers should thoroughly review family medical histories and consider thyroid screening in patients with suspicious symptoms or findings before initiating therapy

NAFLD is a condition in which excess fat accumulates in the liver, and it is often associated with type 2 diabetes

Topical Administration (Most Common) The most widely used approach is topical application via DMSO (dimethyl sulfoxide): Dissolve 3-5mg Dihexa in a few drops of DMSO Apply to forearm skin (DMSO acts as a carrier to drive the peptide through the skin) DMSO concentration: ~20-30% in the solution Pros: Effective absorption, avoids injection Cons: DMSO has a strong garlic-like odor that can transfer to breath/skin Starting Dose Begin at 1-3mg topically to assess response Work up to 3-5mg if tolerating well Cycling Protocol Dihexa appears to have lasting effects that persist after stopping likely due to synaptogenesis (new connections don't disappear when you stop)