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Sustainable weight management is best achieved through a combination of dietary change, physical activity, and behavioural support, with pharmacotherapy used as an adjunct where clinically indicated and in line with NICE guidance

No lethal dose has been established in animal studies, and the peptide appears to have wide safety margins

They can help patients lose 10-20% of their bodyweight in six to 12 months when they make lifestyle changes, such as eating healthy foods and exercising