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166 Moreover, the safety and efficacy of goflikicept, a novel IL-1 blocker, are currently being evaluated in a phase II clinical trial (NCT05673902)

Abbreviations CAI: Chronic ankle instability GLP1-RAs: Glucagon-like peptide-1 receptor agonists FAAM: Foot and ankle ability measure FAOS: Foot and ankle outcome score CAIT: Cumberland ankle instability tool ADL: Activities of daily living T2DM: Type 2 diabetes LAS: Lateral ankle sprain IAC: International Ankle Consortium BAL: Balance training HIP: Hip strengthening BMI: Body mass index CI: Confidence interval References Delahunt E, Bleakley CM, Bossard DS, et al

To illustrate the value of a biosimilar in this space, Biogen referenced in its press release a report by the Association for Accessible Medicines which states that spending on therapies for autoimmune diseases has consistently increased by 10% to 25% each year over the past decade