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2023;13(4)e23.00506
GPX4 is a crucial selenoprotein that converts toxic lipid hydroperoxides (L-OOH) on the cytoplasmic membrane to non-toxic lipid alcohol (L-OH) by utilizing GSH, thus preventing the accumulation of lipid peroxidation to protect cells from ferroptosis (191)
The focus on these specific strategies in research and therapeutic development highlights their potential to significantly enhance efficacy and outcomes
Q&A: How Specific GLP-1s Impact Different Patient Populations | ASHP Midyear Jennifer Clements, PharmD, BCACP, BC-ADM, BCPS, CDCES, FADCES, FCCP, discussed current GLP-1 medication offerings and how each impacts patients differently
The theoretical concern around HGF/c-Met-mediated cellular growth means medical monitoring is particularly important
ABSTRACT: Since the approval of the first dipeptidyl peptidase-4 (DPP-4) inhibitor in the United States in 2006, the use of these agents as second-line oral antihyperglycemic therapy in type 2 diabetes management has been established
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