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Eng et al., J Biol Chem, 1992 Parkes et al., Diabetes Care, 2013 #GLP1 #DrugDiscovery #FromBenchToBedside #NephMadness #MedicalEducation #Endocrinology #Nephrology GLP-1 Receptor Agonists from Gila Monster Venom GLP-1: from lizard venom to modern medicine One of the most fascinating origin stories in pharmacology
Degraded carrageenan causing colitis in rats induces TNF secretion and ICAM-1 upregulation in monocytes through NF-kB activation
Protein: the non-negotiable foundation Protein intake determines whether you lose mostly fat or a mix of fat and muscle
Food and Drug Administrations compassionate use program, according to STAT News
The database captures a wide array of data including demographics, drug details, indications, outcomes, adverse reactions, sources, and therapies
A further 1 to 3 hour delay may flatten the Cmax without substantially changing total AUC exposure, based on the drug's absorption-rate limited pharmacokinetics described in its FDA label [3]
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