tirzepatide e semaglutide EASD 2023: meta-analysis shows superiority to What Are the Side Effects

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Overall, tirzepatide and semaglutide share a very similar side effect profile, particularly for digestive issues like nausea, diarrhea, abdominal pain, and dyspepsia

These precautions are in place to ensure the safe and effective use of the medication, adhering to regulatory guidelines for its approved uses

this effect may counteract the cardiovascular complications by the reduction of the systemic inflammation ( Figure 1 3.2 GLP1-RAs and AMPK GLP-1 (Glucagon-like peptide 1) is an incretin hormone, secreted from L-cells of the small intestine in a glucose-dependent manner, that enables stimulation of insulin secretion, increases pancreatic -cell mass, and inhibits glucagon secretion and gastric emptying, thereby reducing postprandial glycemia

Patterns that show up consistently: Cognitive Effects (Most Reported) Improved verbal fluency words come faster, conversations feel sharper Enhanced pattern recognition connecting ideas across domains more fluidly Better spatial memory navigation, visualization, and spatial reasoning Raw cognitive "horsepower" distinct from the mood/clarity effect of Semax/Selank

Of note, only small number of sudies investigated this outcome with heterogenity in inclusion criteria among study populations, and differences in AOX combinations and SDF assays used