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Obesity is a well-established risk factor for anovulation, irregular menstrual cycles, and polycystic ovary syndrome (PCOS), conditions that significantly impair fertility
Estrogen plays a crucial role in stimulating the growth of the uterine lining during the first half of the menstrual cycle
Official storage guidance will be released alongside the MHRA-approved product information
If a person tolerates it well, a doctor will likely recommend increasing the initial weekly dose from 2.5 milligrams (mg) to 5 mg after this period
This concern is less relevant for patients using subcutaneous methotrexate injections
Even the same drug can have different storage requirements before and after initial use
