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There is no definitive clinical data on this, but user reports suggest that morning injections may produce more daytime bloating while evening injections shift the peak GI effects to overnight (when you are sleeping and not eating)

However, if taking it on an empty stomach causes mild gastrointestinal upset, taking it with a small, light carbohydrate snack can mitigate this issue without severely compromising absorption

It is not recommended as a first-line therapy in BED, although modest weight loss may confer secondary psychological benefit [142]

The recent surge in public awareness around GLP-1s is largely due to FDA approval for new indications, particularly weight management

Recent trials show that overweight or obese patients saw a 14.9% reduction in body weight after taking once-weekly semaglutide 2.4 mg for 68 weeks, compared to a 2.4% reduction in body weight for the control [24]

In addition, the programs emphasis on better coordinated care has led to greater access to important behavioral health services