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That framing can be misleading

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Seek medical advice if temperature consistently exceeds 38.5C, sweating severely disrupts sleep, or palpitations accompany flushing

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Risk ratios (RR) for nonfatal myocardial infarction estimates according to direct (DPP-4 inhibitors, GLP-1RA and SGLT-2 inhibitors against placebo) and indirect (DPP-4 inhibitors vs GLP-1RA or SGLT-2 inhibitors, and GLP-1RA vs SGLT-2 inhibitors) comparisons