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Blood 120, 17171725
Salvianolic acid B modulates the expression of drug-metabolizing enzymes in HepG2 cells
Clinically validated biomarkers of OS, such as F2-isoprostanes (which indicate lipid peroxidation), 8-OHdG (which indicates DNA damage), and the activities of redox enzymes like superoxide dismutase (SOD) and glutathione peroxidase (GPx), show strong correlations with disease progression and end-organ complications
The relatively stable MCV and MCH suggest normocytic normochromic indices despite the hemoglobin reduction, potentially indicating hemolytic mechanism rather than deficiency anemia [53]
BID regulation by p53 contributes to chemosensitivity
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