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[63] However, prolonged consumption of non-steroidal anti-inflammatory drugs, mainly aspirin, induces hepatotoxicity by increasing the level of biochemical parameters (AST, ALT, and LDH) and decreasing the antioxidant defense system

W., Rush, D., & Rosenberg, I

It is this metabolite that exerts the toxic effect on the liver

Symptoms can include rash, itching, swelling, or difficulty breathing