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doi: 10.3168/jds.S0022-0302(01)74660-7, 92

In the first arm of the Phase II FIREFLY-1 study, treatment with Ojemda elicited a best overall response rate of 51%, which included 28% partial responses

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64 Enzymatic degradation of ECM components (e.g., hyaluronidase) or blockade of ECMintegrin interactions (e.g., FAK inhibitors) can also improve drug penetration and reduce stemness-supportive niches