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Transgenic murine models for cognition Beyond chemical lesion models (scopolamine, 192-IgG-saporin), cognitive research has an arsenal of genetically modified strains that reproduce specific cognitive phenotypes: Alzheimer models 3xTg-AD (LaFerla): triple transgenic APP Swedish, PS1 M146V, tau P301L
After dislodging, rosettes were incubated in wells coated with 0.2% porcine gelatin to allow the non-neural cells to differentially attach 21
Most notably was the impact of MDA and NO and decreased Gpx and zinc, although PCs and MPO, as well as decreased TAC, all contribute to neuropsychiatric symptoms
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