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Studies have also shown promise for other metabolic diseases, including polycystic ovary syndrome (PCOS) and obesity-related cancers

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A Add a second oral agent (such as a sulfonylurea, thiazolidinedione, sodium-glucose cotransporter-2 inhibitor, or dipeptidyl peptidase 4 inhibitor), a glucagon-like peptide-1 (GLP-1) receptor agonist, or basal insulin if metformin at a maximum tolerated dose does not achieve the HbA1c target over 3 months

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Appetite and craving control tend to build over two to three weeks of consistent use

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