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Carcinogenesis 1987
"In the brain, it's thought to reduce food intake by some element of appetite suppression," says Evan Nadler, MD, MBA , former co-director of the obesity program at Children's National Hospital and current adjunct associate professor at George Washington University
Diabetes Metab J (2020) 44(1):1132
(PubMed) Stephens NG, Parsons A, Schofield PM, Kelly F, Cheeseman K, Mitchinson MJ
The disruption of the gut RvD5n-3 DPA-IL-10 axis is a key mechanism by which P.g weakens the gut barrier and permits its arthritogenic actions ( P.g also exacerbates inflammatory bowel disease (IBD) by directly degrading the tight junction protein ZO-1 via its gingipains, and by altering gut microbiota to expand IL-9-producing CD4+ T cells, which drive intestinal inflammation (Tsuzuno et al., 2021
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