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Lipid peroxidations byproducts, such as 4-hydroxynonenal or malondialdehyde, can react with lysine amino groups, histidine imidazole groups, or cysteine sulphydryl groups to damage proteins ( 2 O 2 -and/or OCl-mediated mechanism

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33 More recently it has been demonstrated that EphA4, a member of the Eph family of receptor tyrosine kinases, may interact with the GHR

H 2 O 2 stimulates CBS and GCS and inhibits MS and BHMT

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