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If you follow a vegan diet, B12 is not found naturally in fruit, vegetables or grains, so fortified foods or a supplement matter more, and seaweed, spirulina and similar products are not reliable sources

A metabolism-focused framework can help regulators and investigators by making the therapeutic claim testable: the product should have a defined metabolic target, a reproducible potency assay, a biologically plausible delivery window and biomarkers showing that the target changed in treated patients

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