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The National Institutes of Health Office of Dietary Supplements has not set a Tolerable Upper Intake Level for B12 precisely because no reliable evidence of harm from high intakes has been established in healthy people
However, raw cultured dairy, such as yogurt or kefir, is high in probiotics, which can support bowel function
As dosage levels increase, appetite suppression and weight-loss effects often become more pronounced
The Endocrine Society study found that many patients who start these medications eventually discontinue them, only to return later
Our 1000mg dose is double that studied threshold
Other authors report no conflict of interest
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