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Physiol., American Physiological Society 110, 774780 4 Hsieh, M.-J., Lee, C.-H., Chueh, H.-Y., Chang, G.-J., Huang, H.-Y., Lin, Y., et al
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Without intrinsic factor, oral supplements won't work, making injectable B12 for humans often necessary
Supplied as a powder for laboratory investigations into NAD+-related metabolism, methylation pathway markers, and energy-regulation mechanisms in controlled experimental models
It is well-tolerated in animal and early clinical studies, even at multi-milligram doses [12]
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