Abstract Type 2 diabetes mellitus is increasingly conceptualized as an immunometabolic disorder in which hyperglycemia, insulin resistance, oxidative stress, and chronic low-grade inflammation interact synergistically to accelerate vascular and end-organ complications
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In fact, insulin was the first peptide ever made in a lab by scientists (called a synthetic peptide), and it's been used to treat people with type 1 diabetes since 1923
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