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Step 3: Perform the visual inspection After the medication has cooled in the refrigerator for 30-60 minutes, remove it and perform the visual inspection described above

Over a multi-week protocol, this systematic underdosing compounds, potentially invalidating research outcomes

Determination of serum biochemical parameters Serum BUN (mg/dl), creatinine(mg/dl), uric acid(mg/dl), Ca (mg/dl), P(mg/dl) and total protein (g/dl) were measured at the end of the study by an enzymatic colorimetric assays with a DIRUI (CS-T240, China) auto-clinical chemistry-analyzer and commercial diagnostic kit Biosystem company, Spain

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A pill bottle does not require refrigeration and takes minimal space in luggage