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Protocatechuic acid alleviates dextran-sulfate-sodium-induced ulcerative colitis in mice via the regulation of intestinal flora and ferroptosis

If a dose is missed, it must be administered within five days or omitted entirely

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Plasma KPV concentrations following oral administration remain below 5 ng/mL in most animal studies, indicating minimal bioavailability

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Long-term use: Clinical trials only ran 12 weeks, so long-term safety data (6+ months continuous use) comes from anecdotal reports