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Immunity 48, 147160.e7
In this regard, the activation of Orai/STIM as well as store-operated Ca 2+ entry pathways mediates Ca 2+ influx through plasma membrane channels following the depletion of intracellular Ca 2+ stores via IP3 receptor-mediated Ca 2+ i release from the SR
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More recently, a 2024 report titled "Assessing the Economic Impact of Obesity on Employers" found that untreated obesity in the workforce costs $146.5 billion in additional medical expenses each year, along with significant productivity losses tied to absenteeism, presenteeism, and disability
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