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Also, the following risk factors can increase the chance of developing vitamin B-12 deficiency: Alcohol abuse Smoking Certain prescription medications, including antacids and some type 2 diabetes drugs Having an endocrine-related autoimmune disorder, such as diabetes or a thyroid disorder Eating a vegetarian or vegan diet Certain gastrointestinal disorders, such as crohns disease Gastric bypass or the removal of parts of the stomach Aging Benefits of B-12 Shots There are several reasons to consider getting a B-12 shot, including: Reduced risk of vitamin B-12 deficiency and associated complications The most obvious benefit of receiving vitamin B-12 shots is treating a vitamin B-12 deficiency and avoiding its associated symptoms

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After initial repletion, a maintenance dose is given, often 1,000 mcg intramuscularly every month or every 2 to 3 months, to prevent recurrence of deficiency

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Compounds that enhance fat metabolism often simultaneously affect glucose homeostasis, protein synthesis, bone metabolism, cardiovascular function, and endocrine balance