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Under hyperglycemic conditions, RGCs exhibit significant mitochondrial impairment, including cristae dissolution, swelling, vacuolar degeneration, elevated reactive oxygen species (ROS) production, and diminished mitochondrial membrane potential (MMP) [68, 69]
R.GohilK.BairdD
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(PubMed) Stanley CA
This energy dip is a documented side effect tied to calorie deficit, medication dose escalation, and shifts in how your body fuels exercise
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