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10.1002/ajmg.b.32421 28 KomatsuM.WaguriS.UenoT.IwataJ.MurataS.TanidaI.et al
The half-life refers to the time it takes for half of the drug to be eliminated from the body
The quality of the included studies was assessed by a third reviewer using primary data extraction
The glucagonostatic characteristics of GLP-1 RA could prove to be more relevant to individuals with beta cell deficiency [51] which contrasts with type 2 diabetes where beta cell dysfunction and impaired incretin effect may dominate [52]
Quick Answer: Semaglutide is associated with an increased risk of gallstone formation, with clinical trials showing cholelithiasis occurring in approximately 1.6% of treated patients compared to 0.7% receiving placebo
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