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Newer therapies are emerging and currently under study for the management of HE targeting traditional mechanisms of ammonia clearance in addition to novel mechanisms related to altering gut microbiome, reducing inflammation and oxidative stress, protecting endothelial integrity, and modifying neuronal responses (Fig
10.3389/fphys.2021.761481 122
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Many social settings are based around food
Novo Nordisk has released key findings from REDEFINE 1, a phase 3 study that is part of the global REDEFINE program
These reports lack the controls needed to draw reliable conclusions
Yang, G
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