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Studies have demonstrated low blood levels of ergothioneine in patients with mild cognitive impairment and dementia [7-9]
In Phase 2, participants were randomized to multiple doses, such as: 1 mg fixed dose 4 mg, starting at 2 mg or 4 mg 8 mg, starting at 2 mg or 4 mg 12 mg, starting at 2 mg All doses were administered subcutaneously once weekly, and dose escalation was intended to improve tolerability
It is available through research peptide suppliers for investigational use
There are two specific tyrosine residues at the C-terminal end of IR: IRY1328 and 1334
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