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6 High-throughput approaches to disease-specific drug discovery Clinical drug trials notoriously report poor outcomes, in part because drug discovery, development, and pre-clinical research have typically relied on non-mammalian model systems that lack important genetic and physiological features that are unique to the human brain

In that work, co-immunoprecipitation analysis showed reduced binding between caveolin-1 and eNOS, an interaction normally responsible for limiting eNOS activity

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Functional immobilization of plant receptor-like kinase onto microbeads towards receptor array construction and receptor-based ligand fishing