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Semaglutide, known by its brand names like Ozempic or Wegovy, is a GLP-1 receptor agonist that has transformed weight management, particularly for individuals with obesity or type 2 diabetes

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The observation that GIPR antagonism also sensitized to the non-incretin-based weight loss drug Cagri opens potential new avenues for therapeutic exploration

Pyrazole-triazole hybrid analogs as selective cyclooxygenases-2 (COX-2) inhibitors with cardioprotective effects As previously discussed, the sulfonyl/sulfonamide motif is a characteristic pharmacophore group for selective COX-2 inhibition

Journal of Aging Science

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