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If left unmonitored or untreated, approximately one-third of these chronically infected individuals will develop end-stage liver disease, such as cirrhosis or HBV-related HCC (HBV-HCC) 1,2,3,4 , which is associated with more than 600,000 deaths annually 5,6

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Abstract Melanin, a ubiquitous dark pigment, plays important roles in the immune system, including scavenging reactive oxygen species formed in response to ultraviolet radiation absorption, absorbing metals, thermal regulation, drug uptake, innate immune system functions, redox, and energy transduction

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Vitamin D deficiency: a worldwide problem with health consequences