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As one of the most important dopamine-replacement therapies for PD, L-DOPA is commonly given with carbidopa to improve bioavailability and avoid early conversion into dopamine before penetration into the brain (Gandhi and Saadabadi, 2025)

5HLM | pdb_00005hlm Crystal structure of avidin complex with a ferrocene biotin derivative This is version 1.4 of the entry

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Intriguingly, the mechanisms of oxidative phosphorylation-related genes upregulation are cell type specific