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Advantages: Greatest long-term weight loss (2540%) Strong improvements or resolution of diabetes and other conditions Considerations: Invasive with incisions Longer recovery (26 weeks) Higher surgical risks Requires lifelong dietary adjustments and vitamin supplementation GLP-1 Medications : Powerful, Non-Surgical Support GLP-1 receptor agonists (such as semaglutide and tirzepatide) are injectable medications that help reduce appetite, improve insulin sensitivity, and support weight loss

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SSRIs (like Zoloft or Lexapro) powerfully suppress REM sleep

Key psoriatic inflammatory cytokines include IL-23, IL-17, IL-22, IFN-, IL-6, and TNF-