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Rising cases of obesity, unhealthy diets, and lack of physical activity are major contributors to the growing burden of type 2 diabetes

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2000 in Hormone Research showed that 21-day oral AOD-9604 (500 mcg/kg/day) reduced body weight gain by roughly 50% in obese Zucker rats with no insulin sensitivity penalty

doi: 10.1111/ijpo.12495 21 RomarizLMde MeloAACFinneganEMesquitaYJanovskyCCPS

Exogenous SAMe supplement increased the GSH level in the liver and alleviated the liver damage (7, 56, 59)

The peptide accelerates early collagen organization and stimulates expression of the EGR-1 gene along with its repressor NAB2, creating a regulatory feedback loop that prevents excessive fibrosis while promoting organized tissue remodeling