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JUN, VEGFA, IL1B, CD4, STAT3, MAPK3, MMP2, ICAM1, CDC42, MAPK8, MDM2, LCK, MCL1, and HDAC1 were identified as the core targets sorted by degree (Figure 11B), which also confirmed the multitargeting of FRP against AD

The CTL delineates the upper and lower temperature limits beyond which an organism cannot sustain physiological activities, typically resulting in mortality