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Older eggs often have DNA damage
PMC 1263308
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M., Vazquez, A., Kerrigan, J
Upon recruitment to developing plaques, monocytes encounter many inflammatory stimuli such as damage associated molecule patterns (DAMP), oxLDL, and IFN that trigger inflammatory cascades after engagement with toll-like receptors (TLR), scavenger receptors and cytokine receptors, respectively
Anything higher than that quickly becomes too much volume for one subQ site, which is why oral capsules are the standard route
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