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Tryptophan Metabolism in Central Nervous System Diseases: Pathophysiology and Potential Therapeutic Strategies

Costa DL, Diniz JB, Requena G, Joaquim MA, Pittenger C, Bloch MH, et al

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A realistic UK approval window is late 2027 to mid 2028

The associated phenotype includes fibrosis, cholestasis, jaundice, bile duct proliferation, and elevated GT and ALP

Key quality indicators include: the pharmacy conducts in-house stability testing on their specific formulations, they perform sterility testing on each batch, they follow USP 797 guidelines for sterile compounding, and they can provide certificates of analysis upon request