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J Clin Oncol 43 , (2025)

But, patients need training from a healthcare provider on how to do it right

doi:10.1016/j.bbagen.2012.10.012 Ballatori N, Krance SM, Notenboom S, Shi S, Tieu K, Hammond CL

When neurological symptoms are present, more intensive treatment is required: 1 mg hydroxocobalamin on alternate days until no further improvement occurs, followed by maintenance therapy every two months

0:22In published chemical data, it puts it at about 20 to 50 milligrams per milliliter of water