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The obesity medicine community is divided on whether dose tapering before discontinuation provides meaningful benefit
As a GLP-1 receptor agonist and GIP receptor agonist, it works by enhancing insulin sensitivity, reducing blood sugar levels, and increasing feelings of fullness, which contributes to weight loss
Dose reduction after reaching goal weight Once you reach your target weight, many prescribers reduce the dose rather than stopping abruptly
Pinto et al., 2012
(1990) "L-carnitine and platelet aggregation in uremic patients subjected to hemodialysis." Nephron , 55, p
However, the modest effect does not negate the potential value of these drugs, especially for conditions where few effective treatment options exist, for example, dementia, Al-Aly said
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