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These limitations primarily stem from systemic toxicity, poor pharmacokinetics, and inadequate tumor penetration, compounded by the metabolic plasticity of cancer cells [28, 29]
GPX4 uses GSH to eliminate the formation of phospholipid hydroperoxides (PLOOH), thus inhibiting ferroptosis[23, 24]
Rybelsus : This is an oral tablet form of semaglutide taken once daily
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127 Wang, W
85 MTX requires regular monitoring to optimize dosing and assess its immunosuppressive and hepatotoxic effects through frequent blood tests (monthly, initially)
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