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Tesamorelin is generally more expensive per month of therapy than Sermorelin

2 Challenges of oral delivery The low pH of 1.5-3.5 in the stomach unfolds many proteins and activates pepsin, which rapidly cleaves peptide bonds

The phase 2 study to evaluate the efficacy, safety and tolerability of maridebart cafraglutide is currently ongoing (ClinicalTrials.gov number, NCT05669599)