Diabetes 58: 2148-2161, 2009
The data were, however, not compatible with a protective intention-to-treat effect. They concluded: Randomized trials using MALO as an outcome might be unfeasible, motivating further large observational studies using appropriate methodology to further delineate the effect of GLP1 agonists on the risk of MALO, complementing future phase 3 trials of GLP1 agonists.
For patients with a BMI over 35, or over 30 with related conditions like type 2 diabetes, sleep apnea, or high blood pressure, medication alone rarely produces the long-term result they are hoping for
This long half-life means timing variation within a 24-48 hour window does not materially affect drug exposure or efficacy in clinical studies
, L-
Shares of the company are up about 4% this morning following the news