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p53 is an important tumor suppressor gene, and the p53 protein serves a key role in a number of physiological processes such as cell cycle regulation, DNA repair and cell death (68)

Identification of a Novel microRNA-141-3p/Forkhead Box C1/-Catenin Axis Associated With Rheumatoid Arthritis Synovial Fibroblast Function In Vivo and In Vitro

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The stabilization level depends heavily on whether treatment created structural dermal improvements supporting ongoing collagen synthesis or merely provided temporary stimulation requiring continuous application

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