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For type 2 diabetes, NICE-recommended alternatives include metformin (first-line), SGLT2 inhibitors, DPP-4 inhibitors, and insulin therapy, each with distinct mechanisms and side-effect profiles

Dosage Effects Different doses produced different results

Indeed, Guerriere pointed out the quarterly results were influenced by one-off events, such as a more moderate flu season and a severe winter that kept patients home and out of the emergency department as lowering costs

Some more severe, but rare, side effects that can occur are low potassium levels, muscle cramps, irregular heartbeat, chest pains, or blurred vision

Journal of Controlled Release , 2026