The CCK-8 assay demonstrated that sermorelin significantly inhibited glioma cell growth in both a dose- and time-dependent manner
Hodis E, Watson IR, Kryukov GV, Arold ST, Imielinski M, Theurillat JP, Nickerson E, Auclair D, Li L, Place C, Dicara D, Ramos AH, Lawrence MS, Cibulskis K, Sivachenko A, Voet D, Saksena G, Stransky N, Onofrio RC, Winckler W, Ardlie K, Wagle N, Wargo J, chong K, Morton DL, Stemk-Hale K, Chen G, Noble M, Meyrson M, Ladbury JE, Davies MA, Gershenwald JE, Wagner Sn, Hoon DSB, Shadendorf D, Lander ES, Gabriel SBl, Getz G, Garraway LA, Chin L
Managing initial irritation is straightforward
Supplementation ensures adequate levels to prevent complications like nerve damage or anemia
Starting at a lower dose and titrating gradually may help reduce discomfort
Rapid improvement in glucose control has been associated with a temporary worsening of diabetic retinopathy