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Acknowledgements This work was financially supported by the National Natural Science Foundation of China (32172505 to J.L., 32272484 to H.P., 323B2055 to K.X.), the National Key Research and Development Program of China (2019YFE0114200 to H.P.), and the Natural Science Foundation of Jilin Province (20230101156JC to J.L.)

PMCID: PMC7447324

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These injuries occur during explosive movements like sprinting, kicking, or rapid hip flexion

In rare monogenic disorders such as HD, evidence from patients with HD and rodent models suggests that dysfunctional BDNF-TrkB signalling is involved in the disorder development 10