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In our study, we observed the senescence of RPE cells despite the concomitant induction of autophagy following GSH depletion
LousseJCDefrereSVan LangendoncktAGrasJGonzalez-RamosRColetteSet al
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In the phase 1b trial, decreased appetite was reported by every participant in the 2.4 mg cohort and early satiety by two-thirds
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