Serum samples provided a more practical and simpler choice for disease monitoring, which was very important in clinical practice
Overall, the effects of Ser/Gly/Thr metabolism on macrophage polarization are mainly mediated by changes in one-carbon metabolic flux, methyl donor availability, and redox homeostasis, and the resulting outcome is often manifested as threshold regulation of inflammatory transcriptional programs and alterations in phenotypic stability
As a non-selenium cysteine-containing GPX, GPX7 encodes cysteine (Cys57 and Cys86) at its catalytic site
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G.Jr.BladtF.BirchmeierC.et al